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Canine gene

FGF4 RETROGENE ON CFA12

Human counterpart: FGF4

FGF4 RETROGENE ON CFA12 is a gene catalogued in the canine genome. Here is its canonical identity across the genomics world and, where documented, its human counterpart.

In the reference databases

FGF4 RETROGENE ON CFA12 as it is catalogued across the genomics world. Each link is the canonical record, so this gene composes with everything those resources know.

The human counterpart

In humans, this gene's counterpart is FGF4. That ortholog is what connects FGF4 RETROGENE ON CFA12 to a century of human medical genetics.

In people, variants in the FGF4 gene are reported as pathogenic in ClinVar but not yet at our 3★ expert-panel bar (criteria-provided submissions can exist without expert-panel review). The evidence is limited, not that variants here are benign.

In dogs, 20 of 107 Dog10K variants in this gene sit at a position kept conserved across 241 mammals (the exhaustive scan), candidates worth a closer look, never a diagnosis.

Research tools for this gene

Lookup and discovery are candidate-framed research surfaces. Classification renders AVCG grades we cite; Sniff does not score variants with a model of its own.

On the numbers

Per-breed allele frequencies across the atlas are surfaced for the trait loci Sniff has verified a direction-of-effect for. For FGF4 RETROGENE ON CFA12 we show the cited identity and disease associations, and we would rather show you exactly that than a frequency we cannot yet interpret honestly. See the gene catalog for trait loci with frequency views and every disease-linked gene page.

How to cite this page

Gene identity and disease associations are grounded in OMIA (CC-BY) and the open Sniff Atlas. Full citation formats at sniff.world/cite.

Last updated
Sources: OMIA · Sniff gene crossrefs · Ensembl / NCBI / HGNC · ClinVar (Landrum 2018) · Dog10K (Meadows 2023) · Zoonomia 241-way phyloP (Christmas 2023)